Across TCGA patient cohorts, TAS2R19 mutation is significantly associated with the RNA expression of many other genes, with 132 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R19-associated genes across cancer lineages are RNA5SP309, PRAC1, and PPP1R26P5. Each is linked with TAS2R19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R19-to-partner and partner-to-TAS2R19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R19→partner) and Y-score (partner→TAS2R19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP309 →	+0.705	+5.669	<.001	.003	3	2
LUSC	PRAC1 →	+1.189	+3.157	<.001	.004	3	2
CESC	PPP1R26P5 →	+0.012	+5.669	<.001	.003	3	2
LUAD	SNRPGP7 →	+0.249	+4.303	<.001	.009	3	2
UCEC	MLLT10P2 →	+0.389	+3.920	<.001	<.001	3	2
UCEC	TEMN3-AS1 →	+0.386	+3.551	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 132 associations by consensus.

Exploration

TAS2R19 survival (RNA) · tumor vs normal (RNA) · all TAS2R19 data types