Across TCGA patient cohorts, TAS2R19 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R19-associated genes across cancer lineages are MEP, Macrophages M1, and Eosinophils. Each is linked with TAS2R19 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R19-to-partner and partner-to-TAS2R19 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R19→partner) and Y-score (partner→TAS2R19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEP →	+0.057	+3.010	<.001	.020	3	2
UCEC	Macrophages M1 →	+0.019	+3.328	.029	.012	3	1
UCEC	Eosinophils →	-0.065	-2.967	.041	.037	1	1
UCEC	Melanocytes →	-0.012	-2.946	.040	.037	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

TAS2R19 survival (RNA) · tumor vs normal (RNA) · all TAS2R19 data types