Across TCGA cell cohorts, TAS2R19 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,495 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TAS2R19-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Microtubule polymerization, and DNA biosynthetic process. Each is linked with TAS2R19 in more than 11 cancer types. Because this analysis shows association rather than direction, both TAS2R19-to-partner and partner-to-TAS2R19 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R19→partner) and Y-score (partner→TAS2R19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of DNA metabolic process →	+0.053	+0.472	<.001	<.001	3	12
BONE	Microtubule polymerization →	+0.107	+0.332	.008	.009	3	12
BLOOD_Leukemia	DNA biosynthetic process →	+0.069	+0.422	<.001	<.001	3	12
LARGE_INTESTINE	Microtubule polymerization or depolymerization →	+0.081	+0.171	<.001	<.001	3	12
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.070	+0.339	<.001	.005	3	12
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.142	+0.243	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,495 associations by consensus.

Exploration

TAS2R19 survival (RNA) · tumor vs normal (RNA) · all TAS2R19 data types