TAS2R16

Across TCGA patient cohorts, TAS2R16 protein abundance is significantly associated with the RNA expression of many other genes, with 1,395 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAS2R16-associated genes across cancer lineages are BIN2, SIGLEC10, and C1orf162. Each is linked with TAS2R16 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R16-to-partner and partner-to-TAS2R16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAS2R16 versus BIN2 in GBM, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R16→partner) and Y-score (partner→TAS2R16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BIN2 →	+1.444	+0.523	<.001	.007	3	2
GBM	SIGLEC10 →	+1.905	+0.490	<.001	.002	3	2
GBM	C1orf162 →	+1.380	+0.556	.002	.005	3	2
GBM	CD53 →	+1.803	+0.593	<.001	.001	3	2
GBM	SLC7A7 →	+0.996	+0.581	.008	.006	3	2
GBM	C1QC →	+1.748	+0.660	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,395 associations by consensus.

TAS2R16 vs BIN2 — GBM

Explore this scatter interactively →