TAS2R10

Across TCGA cell cohorts, TAS2R10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,486 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TAS2R10-associated GO terms across cancer lineages are Regulation of telomere maintenance, Regulation of alternative mRNA splicing, via spliceosome, and mRNA transport. Each is linked with TAS2R10 in more than 15 cancer types. Because this analysis shows association rather than direction, both TAS2R10-to-partner and partner-to-TAS2R10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of telomere maintenance grouped by TAS2R10-low versus TAS2R10-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R10→partner) and Y-score (partner→TAS2R10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of telomere maintenance →	+0.059	+0.228	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of alternative mRNA splicing, via spliceosome →	+0.102	+0.410	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	mRNA transport →	+0.098	+0.408	.001	.004	3	16
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.141	+0.387	<.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.102	-0.374	<.001	.003	3	14
BONE	Pre-mRNA catabolic process →	+0.227	+0.424	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,486 associations by consensus.

Regulation of telomere maintenance by TAS2R10 expression — URINARY_TRACT

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