TAS2R1

Across TCGA patient cohorts, TAS2R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,350 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TAS2R1-associated GO terms across cancer lineages are Protein stabilization, Establishment of protein localization to membrane, and Organelle disassembly. Each is linked with TAS2R1 in more than 15 cancer types. Because this analysis shows association rather than direction, both TAS2R1-to-partner and partner-to-TAS2R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by TAS2R1-low versus TAS2R1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R1→partner) and Y-score (partner→TAS2R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein stabilization →	+0.070	+0.047	<.001	<.001	3	16
STAD	Establishment of protein localization to membrane →	+0.066	+0.046	<.001	<.001	3	15
STAD	Organelle disassembly →	+0.070	+0.043	<.001	<.001	3	15
ESCA	Positive regulation of proteolysis involved in protein catabolic process →	+0.064	+0.078	<.001	.003	3	15
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.068	+0.041	<.001	<.001	3	15
STAD	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.064	+0.040	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,350 associations by consensus.

Protein stabilization by TAS2R1 expression — STAD

Explore this box plot interactively →