TAS1R1

Across TCGA cell cohorts, TAS1R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,268 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TAS1R1-associated GO terms across cancer lineages are Protein-DNA complex organization, Negative regulation of syncytium formation by plasma membrane fusion, and Negative regulation of cytoplasmic pattern recognition receptor signaling pathway. Each is linked with TAS1R1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TAS1R1-to-partner and partner-to-TAS1R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein-DNA complex organization grouped by TAS1R1-low versus TAS1R1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS1R1→partner) and Y-score (partner→TAS1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein-DNA complex organization →	+0.058	+0.041	<.001	.002	3	7
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.079	+0.056	.002	.004	3	7
BREAST	Negative regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.061	+0.041	.004	.005	3	6
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.138	+0.167	.008	.003	3	6
PANCREAS	Regulation of organelle assembly →	+0.036	+0.071	.004	.001	3	6
OVARY	Protein-containing complex disassembly →	+0.053	+0.061	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,268 associations by consensus.

Protein-DNA complex organization by TAS1R1 expression — LARGE_INTESTINE

Explore this box plot interactively →