Across TCGA patient cohorts, TARS3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,075 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TARS3-associated genes across cancer lineages are TM2D3, DLG2, and SLITRK4. Each is linked with TARS3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TARS3-to-partner and partner-to-TARS3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TARS3→partner) and Y-score (partner→TARS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TM2D3 →	+0.517	+0.424	<.001	<.001	3	4
GBM	DLG2 →	+0.811	+0.297	<.001	<.001	3	4
GBM	SLITRK4 →	+0.870	+0.268	<.001	<.001	3	4
BRCA	PTK7 →	-0.817	-0.281	.001	.001	3	3
COAD	CRYAB →	+0.984	+0.389	<.001	.001	3	3
GBM	NRXN2 →	+0.979	+0.302	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,075 associations by consensus.

Exploration

TARS3 survival (RNA) · tumor vs normal (RNA) · all TARS3 data types