Across TCGA patient cohorts, TARS3 mutation is significantly associated with the RNA expression of many other genes, with 1,397 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TARS3-associated genes across cancer lineages are SCARNA21B, TEMN3-AS1, and ATP7BP1. Each is linked with TARS3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TARS3-to-partner and partner-to-TARS3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TARS3→partner) and Y-score (partner→TARS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	SCARNA21B →	+0.306	+6.008	<.001	.002	3	3
CESC	TEMN3-AS1 →	+0.113	+4.516	<.001	.004	3	3
LIHC	ATP7BP1 →	+0.121	+5.758	<.001	.003	3	2
CESC	HBZ →	+0.080	+3.590	.003	.002	3	2
CESC	ZNF733P →	+0.011	+4.247	<.001	.007	3	2
UCEC	DCP1A →	+0.602	+2.906	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,397 associations by consensus.

Exploration

TARS3 survival (RNA) · tumor vs normal (RNA) · all TARS3 data types