TARS2

Across TCGA cell cohorts, TARS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,335 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TARS2-associated GO terms across cancer lineages are Threonyl-tRNA aminoacylation, Aminoacyl-tRNA metabolism involved in translational fidelity, and Ribonucleoside triphosphate biosynthetic process. Each is linked with TARS2 in more than 19 cancer types. Because this analysis shows association rather than direction, both TARS2-to-partner and partner-to-TARS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Threonyl-tRNA aminoacylation grouped by TARS2-low versus TARS2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TARS2→partner) and Y-score (partner→TARS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Threonyl-tRNA aminoacylation →	+0.174	+0.763	<.001	<.001	3	20
LUNG_NSCLC_LUSC	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.153	+1.078	<.001	<.001	3	17
OVARY	Ribonucleoside triphosphate biosynthetic process →	+0.088	+0.695	<.001	<.001	3	14
OVARY	Nucleoside triphosphate biosynthetic process →	+0.085	+0.612	<.001	.001	3	13
SKIN	tRNA aminoacylation for protein translation →	+0.081	+0.745	<.001	<.001	3	13
SOFT_TISSUE	Regulation of translational fidelity →	+0.102	+0.742	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,335 associations by consensus.

Threonyl-tRNA aminoacylation by TARS2 expression — STOMACH

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