TARDBP

Across TCGA cell cohorts, TARDBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,440 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TARDBP-associated GO terms across cancer lineages are Interstrand cross-link repair, DNA-templated DNA replication maintenance of fidelity, and Regulation of chromosome condensation. Each is linked with TARDBP in more than 19 cancer types. Because this analysis shows association rather than direction, both TARDBP-to-partner and partner-to-TARDBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interstrand cross-link repair grouped by TARDBP-low versus TARDBP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TARDBP→partner) and Y-score (partner→TARDBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Interstrand cross-link repair →	+0.100	+0.908	.002	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication maintenance of fidelity →	+0.133	+1.010	<.001	<.001	3	20
OVARY	Regulation of chromosome condensation →	+0.201	+0.597	<.001	.001	3	20
OVARY	DNA-templated DNA replication →	+0.119	+0.629	<.001	<.001	3	20
BONE	Mitotic sister chromatid segregation →	+0.138	+0.687	.004	.003	3	20
BLOOD_Myeloma	Chromosome segregation →	+0.088	+0.717	.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,440 associations by consensus.

Interstrand cross-link repair by TARDBP expression — BONE

Explore this box plot interactively →