TAPT1

Across TCGA patient cohorts, TAPT1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,020 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAPT1-associated genes across cancer lineages are PLS3, CTBP1, and SMIM14. Each is linked with TAPT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TAPT1-to-partner and partner-to-TAPT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAPT1 versus PLS3 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAPT1→partner) and Y-score (partner→TAPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLS3 →	-1.199	-0.593	<.001	<.001	3	5
LSCC	CTBP1 →	+0.497	+0.353	<.001	<.001	3	5
BRCA	SMIM14 →	+1.102	+0.499	<.001	.007	3	5
BRCA	CALU →	-0.561	-0.510	.001	<.001	3	4
GBM	COLGALT1 →	-0.425	-0.242	<.001	<.001	3	4
BRCA	SLC25A4 →	+0.692	+0.581	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,020 associations by consensus.

TAPT1 vs PLS3 — BRCA

Explore this scatter interactively →