TAPT1

Across TCGA cell cohorts, TAPT1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAPT1-associated genes across cancer lineages are CCKAR, CCT8L2, and TLE7. Each is linked with TAPT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAPT1-to-partner and partner-to-TAPT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCKAR grouped by TAPT1-low versus TAPT1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAPT1→partner) and Y-score (partner→TAPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CCKAR →	+0.043	+4.409	<.001	.005	3	1
BLOOD_Leukemia	CCT8L2 →	+0.014	+4.874	<.001	.002	3	1
BLOOD_Leukemia	TLE7 →	+0.032	+4.969	<.001	.003	3	1
LARGE_INTESTINE	PACRGL →	+0.670	+3.082	<.001	.007	3	1
LARGE_INTESTINE	TRHR →	+0.053	+2.839	<.001	.004	3	1
LARGE_INTESTINE	VHLL →	+0.096	+3.478	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CCKAR by TAPT1 expression — BLOOD_Leukemia

Explore this box plot interactively →