TAPT1-AS1

Across TCGA pan-cancer cohorts, TAPT1-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated TAPT1-AS1 data layer compared with 1 for mutation status.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher TAPT1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAPT1-AS1 expression acts as an unfavorable survival marker, although some lineages such as PRAD and SKCM show a favorable association.

CESC, KIRC, and LUAD are the cancer types where TAPT1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	All	0.745	0.874	.002	22	view →
KIRC	DFS	Median	IV	0.238	0.422	.011	20	view →
LUAD	DFS	Quartile	II,III,IV	0.600	0.857	.005	18	view →
THCA	OS	Tertile	II,III,IV	0.703	0.875	.013	16	view →
PRAD	DFS	Tertile	All	0.924	0.850	.023	12	view →
SKCM	OS	Quartile	All	0.412	0.240	.001	11	view →
BLCA	OS	Quartile	IV	0.426	0.807	.013	9	view →
UVM	OS	Quartile	III,IV	0.319	0.825	.012	9	view →
BRCA	OS	Median	II,III,IV	0.934	0.890	.013	9	view →
CHOL	DFS	Quartile	All	0.824	0.148	.026	8	view →
READ	OS	Quartile	IV	0.913	0.461	.022	8	view →
MESO	DFS	Quartile	III,IV	0.128	0.646	.010	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

TAPT1-AS1–CESC (DFS)

Open the CESC breakdown →