TAPBPL

Across TCGA cell cohorts, TAPBPL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,835 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TAPBPL-associated GO terms across cancer lineages are Regulation of antigen processing and presentation, Regulation of antigen processing and presentation of peptide antigen, and Antigen processing and presentation of peptide antigen via MHC class I. Each is linked with TAPBPL in more than 17 cancer types. Because this analysis shows association rather than direction, both TAPBPL-to-partner and partner-to-TAPBPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of antigen processing and presentation grouped by TAPBPL-low versus TAPBPL-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAPBPL→partner) and Y-score (partner→TAPBPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of antigen processing and presentation →	+0.224	+1.883	<.001	<.001	2	18
BONE	Regulation of antigen processing and presentation of peptide antigen →	+1.406	+1.742	<.001	.001	3	17
UPPER_AERODIGESTIVE_TRACT	Antigen processing and presentation of peptide antigen via MHC class I →	+0.233	+1.734	<.001	.001	3	16
LUNG_SCLC	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.244	+1.278	<.001	<.001	3	16
LIVER	Negative regulation of antigen processing and presentation of peptide antigen →	+1.386	+1.753	<.001	.001	3	16
URINARY_TRACT	CD8-positive, alpha-beta T cell activation →	+0.145	+1.602	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,835 associations by consensus.

Regulation of antigen processing and presentation by TAPBPL expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →