Across TCGA patient cohorts, TAP2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,961 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TAP2-associated genes across cancer lineages are ETV7, STAT1, and GBP1. Each is linked with TAP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TAP2-to-partner and partner-to-TAP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAP2→partner) and Y-score (partner→TAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ETV7 →	+1.233	+0.610	<.001	<.001	3	10
HNSC	STAT1 →	+1.784	+0.960	<.001	<.001	3	10
HNSC	GBP1 →	+1.384	+0.613	<.001	<.001	3	10
HNSC	ZBP1 →	+1.424	+0.821	<.001	<.001	3	10
COAD	IRF1 →	+1.318	+0.537	<.001	<.001	3	10
GBM	EPSTI1 →	+1.464	+0.873	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,961 associations by consensus.

Exploration

TAP2 survival (RNA) · tumor vs normal (RNA) · all TAP2 data types