Across TCGA patient cohorts, TAP2 protein abundance is significantly associated with the protein abundance of many other proteins, with 21,155 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TAP2-associated proteins across cancer lineages are PSME2, TAPBP, and TRIM21. Each is linked with TAP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both TAP2-to-partner and partner-to-TAP2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAP2→partner) and Y-score (partner→TAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PSME2 →	+0.537	+0.533	<.001	<.001	3	10
UCEC	TAPBP →	+1.041	+0.937	<.001	<.001	3	10
HNSC	TRIM21 →	+0.416	+0.586	<.001	<.001	3	10
COAD	WARS1 →	+0.927	+0.604	<.001	<.001	3	10
LSCC	STAT1 →	+0.788	+0.748	<.001	<.001	3	10
UCEC	TAP1 →	+0.837	+0.843	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,155 associations by consensus.

Exploration

TAP2 survival (RNA) · tumor vs normal (RNA) · all TAP2 data types