TAP1

Across TCGA cell cohorts, TAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,615 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TAP1-associated GO terms across cancer lineages are Antigen processing and presentation of endogenous antigen, Antigen processing and presentation of endogenous peptide antigen via MHC class I, and Antigen processing and presentation of endogenous peptide antigen. Each is linked with TAP1 in more than 19 cancer types. Because this analysis shows association rather than direction, both TAP1-to-partner and partner-to-TAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antigen processing and presentation of endogenous antigen grouped by TAP1-low versus TAP1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAP1→partner) and Y-score (partner→TAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Antigen processing and presentation of endogenous antigen →	+0.309	+2.262	<.001	<.001	3	20
LIVER	Antigen processing and presentation of endogenous peptide antigen via MHC class I →	+0.377	+3.845	<.001	<.001	3	20
KIDNEY	Antigen processing and presentation of endogenous peptide antigen →	+0.300	+1.714	<.001	.002	3	20
LUNG_NSCLC_LUSC	Antigen processing and presentation of peptide antigen →	+0.205	+2.145	<.001	.002	3	20
LUNG_SCLC	Antigen processing and presentation →	+0.165	+2.683	<.001	<.001	3	19
LIVER	Antigen processing and presentation of peptide antigen via MHC class I →	+0.279	+3.515	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,615 associations by consensus.

Antigen processing and presentation of endogenous antigen by TAP1 expression — BREAST

Explore this box plot interactively →