TAOK3

Across TCGA pan-cancer cohorts, TAOK3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TAOK3 data layer compared with 21 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TAOK3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAOK3 expression acts as an unfavorable survival marker, although some lineages such as GBM and UCEC show a favorable association.

PDAC, COAD, and GBM are the cancer types where TAOK3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.556	0.757	.027	8	view →
COAD	DFS	Median	III,IV	0.829	1.000	.027	6	view →
GBM	OS	Median	All	0.446	0.289	.027	4	view →
UCEC	OS	Tertile	All	1.000	0.835	.015	4	view →
HNSC	OS	Quartile	All	0.849	0.633	.042	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TAOK3–PDAC (DFS)

Open the PDAC breakdown →