TAOK3

Across TCGA patient cohorts, TAOK3 mutation is significantly associated with the RNA expression of many other genes, with 6,101 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAOK3-associated genes across cancer lineages are KCTD9, NDUFAF1, and MTA2. Each is linked with TAOK3 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAOK3-to-partner and partner-to-TAOK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCTD9 grouped by TAOK3-low versus TAOK3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAOK3→partner) and Y-score (partner→TAOK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KCTD9 →	+0.766	+2.283	<.001	<.001	3	4
UCEC	NDUFAF1 →	+0.555	+2.283	<.001	<.001	3	4
UCEC	MTA2 →	+0.493	+2.064	<.001	<.001	3	3
UCEC	AGPAT5 →	+0.533	+1.856	<.001	.004	2	4
UCEC	CWC22 →	+0.461	+2.337	.001	<.001	3	3
UCEC	SFXN1 →	+0.659	+2.584	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,101 associations by consensus.

KCTD9 by TAOK3 expression — UCEC

Explore this box plot interactively →