TAOK3

Across TCGA cell cohorts, TAOK3 mutation is significantly associated with the RNA expression of many other genes, with 342 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAOK3-associated genes across cancer lineages are PRAMEF7, RAB3GAP1, and DESI2. Each is linked with TAOK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAOK3-to-partner and partner-to-TAOK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF7 grouped by TAOK3-low versus TAOK3-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAOK3→partner) and Y-score (partner→TAOK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PRAMEF7 →	+1.052	+4.285	<.001	.003	3	2
LARGE_INTESTINE	RAB3GAP1 →	+0.495	+3.364	.002	.002	3	2
LARGE_INTESTINE	DESI2 →	+0.530	+3.364	.001	.002	3	2
LARGE_INTESTINE	ZNF304 →	+0.655	+3.064	.009	.009	3	2
LARGE_INTESTINE	ABI2 →	+0.872	+3.087	<.001	.006	3	2
LARGE_INTESTINE	PIP5K1A →	+0.638	+3.067	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 342 associations by consensus.

PRAMEF7 by TAOK3 expression — BLOOD_Myeloma

Explore this box plot interactively →