TAOK1

Across TCGA pan-cancer cohorts, TAOK1 Mutation is linked to patient survival in 11 of 34 cancer types, making it a survival-associated TAOK1 data layer compared with 28 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher TAOK1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TAOK1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

OV, THYM, and ACC are the cancer types where TAOK1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.170	0.844	<.001	42	view →
THYM	OS	Median	III,IV	0.103	0.944	<.001	42	view →
ACC	OS	Median	All	0.256	0.809	<.001	36	view →
LUSC	OS	Median	II,III,IV	0.270	0.741	<.001	18	view →
SCLC	OS	Median	II,III,IV	0.260	0.708	.005	15	view →
DLBC	DFS	Median	II,III,IV	0.022	0.837	<.001	12	view →
BRCA	DFS	Median	All	0.585	0.902	.013	10	view →
LIHC	DFS	Median	All	0.091	0.555	<.001	9	view →
SKCM	OS	Median	IV	0.179	0.727	<.001	8	view →
UCEC	DFS	Median	All	0.970	0.890	.040	6	view →
SARC	OS	Median	All	0.239	0.826	.002	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

TAOK1–OV (OS)

Open the OV breakdown →