TAOK1

Across TCGA patient cohorts, TAOK1 mutation is significantly associated with the RNA expression of many other genes, with 2,934 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAOK1-associated genes across cancer lineages are CHAF1B, RBM47, and LEO1. Each is linked with TAOK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAOK1-to-partner and partner-to-TAOK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CHAF1B grouped by TAOK1-low versus TAOK1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAOK1→partner) and Y-score (partner→TAOK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CHAF1B →	+0.502	+1.999	<.001	<.001	3	3
UCEC	RBM47 →	+0.459	+1.776	.005	<.001	3	3
UCEC	LEO1 →	+0.484	+2.595	<.001	<.001	3	3
UCEC	CHAF1A →	+0.524	+2.294	<.001	<.001	3	3
UCEC	PBK →	+0.683	+1.541	.001	.002	3	3
UCEC	RRM2 →	+0.619	+1.928	.002	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,934 associations by consensus.

CHAF1B by TAOK1 expression — UCEC

Explore this box plot interactively →