TAOK1

Across TCGA cell cohorts, TAOK1 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAOK1-associated genes across cancer lineages are C6orf118, TNP1, and MCHR2. Each is linked with TAOK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAOK1-to-partner and partner-to-TAOK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by TAOK1-low versus TAOK1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAOK1→partner) and Y-score (partner→TAOK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.088	+3.115	.006	.004	3	2
BLOOD_Leukemia	TNP1 →	+0.167	+5.569	<.001	.001	3	1
BLOOD_Leukemia	MCHR2 →	+0.034	+4.539	<.001	.007	3	1
BLOOD_Leukemia	SLC35G3 →	+0.044	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR1G1 →	+0.072	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TFDP3 →	+0.011	+5.269	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

C6orf118 by TAOK1 expression — LARGE_INTESTINE

Explore this box plot interactively →