Across TCGA pan-cancer cohorts, TANK-AS1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TANK-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where TANK-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types TANK-AS1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA and LIHC are the cancer types where TANK-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TANK-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	III,IV	−0.071	.033	2	view →
LIHC	All	All	+0.021	.010	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TANK-AS1 RNA expression & survival · all TANK-AS1 data types