TANGO6

Across TCGA cell cohorts, TANGO6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,735 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TANGO6-associated GO terms across cancer lineages are IMP biosynthetic process, Transcription initiation at RNA polymerase I promoter, and Chromosome segregation. Each is linked with TANGO6 in more than 13 cancer types. Because this analysis shows association rather than direction, both TANGO6-to-partner and partner-to-TANGO6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by TANGO6-low versus TANGO6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TANGO6→partner) and Y-score (partner→TANGO6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IMP biosynthetic process →	+0.268	+1.275	<.001	<.001	3	14
PANCREAS	Transcription initiation at RNA polymerase I promoter →	+0.148	+1.253	<.001	<.001	3	14
BLOOD_Lymphoma	Chromosome segregation →	+0.088	+0.718	<.001	<.001	3	14
BREAST	Protein depolymerization →	+0.100	+0.685	<.001	<.001	3	13
BREAST	Establishment of RNA localization →	+0.078	+0.856	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.102	+0.890	.002	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,735 associations by consensus.

IMP biosynthetic process by TANGO6 expression — URINARY_TRACT

Explore this box plot interactively →