TANC2

Across TCGA patient cohorts, TANC2 mutation is significantly associated with the RNA expression of many other genes, with 6,790 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TANC2-associated genes across cancer lineages are HMGN1P31, CDCA2, and FAM72B. Each is linked with TANC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TANC2-to-partner and partner-to-TANC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMGN1P31 grouped by TANC2-low versus TANC2-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TANC2→partner) and Y-score (partner→TANC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	HMGN1P31 →	+0.231	+3.183	<.001	.003	3	5
UCEC	CDCA2 →	+0.754	+1.725	<.001	<.001	3	4
UCEC	FAM72B →	+0.267	+1.450	<.001	<.001	3	4
STAD	LINC02326 →	+0.243	+3.383	<.001	<.001	3	4
UCEC	STOML2 →	+0.341	+1.725	<.001	<.001	3	4
UCEC	SHE →	-0.256	-1.429	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,790 associations by consensus.

HMGN1P31 by TANC2 expression — STAD

Explore this box plot interactively →