TANC2

Across TCGA cell cohorts, TANC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,164 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TANC2-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Dense core granule cytoskeletal transport. Each is linked with TANC2 in more than 14 cancer types. Because this analysis shows association rather than direction, both TANC2-to-partner and partner-to-TANC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by TANC2-low versus TANC2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TANC2→partner) and Y-score (partner→TANC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.067	+1.736	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.077	+1.731	<.001	<.001	3	15
OESOPHAGUS	Dense core granule cytoskeletal transport →	+0.168	+1.487	<.001	<.001	3	14
OESOPHAGUS	Dense core granule transport →	+0.168	+1.487	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Regulation of protein localization to mitochondrion →	+0.135	+2.217	<.001	.001	3	14
BONE	Regulation of intracellular transport →	+0.055	+1.347	.004	.003	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,164 associations by consensus.

Endosomal transport by TANC2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →