TANC1

Across TCGA pan-cancer cohorts, TANC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated TANC1 data layer compared with 26 for mass-spec protein and 12 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TANC1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TANC1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where TANC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.788	0.306	<.001	13	view →
LUAD	OS	Median	All	0.850	0.549	.015	5	view →
UCEC	DFS	Tertile	II,III,IV	0.884	0.465	.044	4	view →
HNSC	OS	Median	All	1.000	0.959	.023	3	view →
PDAC	DFS	Tertile	IV	0.182	0.515	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

TANC1–CCRCC (DFS)

Open the CCRCC breakdown →