TANC1

Across TCGA cell cohorts, TANC1 mutation is significantly associated with the RNA expression of many other genes, with 664 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TANC1-associated genes across cancer lineages are PRAMEF9, TBC1D3H, and BOK. Each is linked with TANC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TANC1-to-partner and partner-to-TANC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRAMEF9 grouped by TANC1-low versus TANC1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TANC1→partner) and Y-score (partner→TANC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PRAMEF9 →	+0.010	+4.087	<.001	.009	3	2
CNS	TBC1D3H →	+0.511	+3.459	<.001	.006	3	2
SKIN	BOK →	+1.320	+3.212	.001	.006	3	2
LUNG_SCLC	MBD3L2 →	+0.447	+3.353	<.001	.001	3	2
BLOOD_Leukemia	DAOA →	+0.014	+2.954	<.001	.005	3	2
LARGE_INTESTINE	RBFA →	+0.677	+2.364	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 664 associations by consensus.

PRAMEF9 by TANC1 expression — URINARY_TRACT

Explore this box plot interactively →