TAMALIN

Across TCGA pan-cancer cohorts, TAMALIN mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TAMALIN data layer compared with 24 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher TAMALIN mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TAMALIN expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where TAMALIN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	All	1.000	0.730	.003	19	view →
LUAD	DFS	Tertile	All	1.000	0.380	<.001	11	view →
CCRCC	OS	Tertile	All	1.000	0.594	.012	8	view →
GBM	OS	Median	All	0.451	0.585	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TAMALIN–LSCC (DFS)

Open the LSCC breakdown →