TAMALIN

Across TCGA cell cohorts, TAMALIN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,304 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TAMALIN-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, RNA splicing, via transesterification reactions, and RNA splicing, via transesterification reactions with bulged adenosine as nucleophile. Each is linked with TAMALIN in more than 11 cancer types. Because this analysis shows association rather than direction, both TAMALIN-to-partner and partner-to-TAMALIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by TAMALIN-low versus TAMALIN-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAMALIN→partner) and Y-score (partner→TAMALIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.094	+0.323	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions →	+0.086	+0.420	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.085	+0.406	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	mRNA splicing, via spliceosome →	+0.085	+0.406	.001	<.001	3	11
OESOPHAGUS	Negative regulation of mRNA processing →	+0.102	+0.638	<.001	.001	3	11
SOFT_TISSUE	Positive regulation of DNA metabolic process →	+0.058	+1.548	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,304 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by TAMALIN expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →