TAMALIN

Across TCGA cell cohorts, TAMALIN mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAMALIN-associated genes across cancer lineages are CFHR2, MS4A4A, and VSIG4. Each is linked with TAMALIN in more than 1 cancer types. Because this analysis shows association rather than direction, both TAMALIN-to-partner and partner-to-TAMALIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by TAMALIN-low versus TAMALIN-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAMALIN→partner) and Y-score (partner→TAMALIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	2
LARGE_INTESTINE	MS4A4A →	+0.136	+3.678	<.001	.009	3	1
LARGE_INTESTINE	VSIG4 →	+0.036	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CFHR2 by TAMALIN expression — LARGE_INTESTINE

Explore this box plot interactively →