TAL1

Across TCGA patient cohorts, TAL1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,486 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TAL1-associated genes across cancer lineages are TEK, MMRN2, and TIE1. Each is linked with TAL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAL1-to-partner and partner-to-TAL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAL1 versus TEK in LSCC, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAL1→partner) and Y-score (partner→TAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TEK →	+1.285	+1.188	<.001	<.001	3	3
HNSC	MMRN2 →	+1.010	+0.645	.001	.004	3	3
LUAD	TIE1 →	+1.191	+1.101	<.001	<.001	3	3
HNSC	ANP32B →	-1.396	-0.886	<.001	.007	3	2
LUAD	DIPK2B →	+0.952	+0.903	.001	.002	3	2
LSCC	ESAM →	+1.072	+1.225	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,486 associations by consensus.

TAL1 vs TEK — LSCC

Explore this scatter interactively →