TAGLN3

Across TCGA patient cohorts, TAGLN3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,342 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAGLN3-associated genes across cancer lineages are ARHGEF35, CPP, and BTG1P1. Each is linked with TAGLN3 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAGLN3-to-partner and partner-to-TAGLN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAGLN3 versus ARHGEF35 in OV, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAGLN3→partner) and Y-score (partner→TAGLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARHGEF35 →	-0.963	-1.315	.008	.003	3	3
OV	CPP →	-2.770	-1.909	.007	.004	3	3
PDAC	BTG1P1 →	+0.652	+0.559	.003	<.001	3	3
PDAC	EBI3 →	+0.687	+0.692	<.001	<.001	3	2
HNSC	SDC1 →	-0.919	-0.558	.009	.006	3	2
HNSC	TBC1D4 →	+0.700	+0.643	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,342 associations by consensus.

TAGLN3 vs ARHGEF35 — OV

Explore this scatter interactively →