TAGLN3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TAGLN3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAGLN3-associated genes across cancer lineages are pDC and Sebocytes. Each is linked with TAGLN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAGLN3-to-partner and partner-to-TAGLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by TAGLN3-low versus TAGLN3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAGLN3→partner) and Y-score (partner→TAGLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECpDC →+0.053+3.008.020.01931
UCECSebocytes →-0.023-3.086.049.01931
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

pDC by TAGLN3 expression — UCEC

Box plot of pDC in TAGLN3-low vs TAGLN3-high samples in UCEC.

Explore this box plot interactively →

Exploration