TAGAP

Across TCGA cell cohorts, TAGAP mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAGAP-associated genes across cancer lineages are IRX4, RPF1, and NARS1. Each is linked with TAGAP in more than 1 cancer types. Because this analysis shows association rather than direction, both TAGAP-to-partner and partner-to-TAGAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IRX4 grouped by TAGAP-low versus TAGAP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAGAP→partner) and Y-score (partner→TAGAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IRX4 →	+0.424	+3.409	.001	.009	3	1
LARGE_INTESTINE	RPF1 →	+0.852	+3.087	<.001	.006	3	1
LARGE_INTESTINE	NARS1 →	+0.776	+3.067	.009	.009	3	1
LARGE_INTESTINE	VAX1 →	+0.618	+3.478	<.001	.002	3	1
LARGE_INTESTINE	FCN2 →	+0.022	+3.415	<.001	.001	3	1
LARGE_INTESTINE	REG1B →	+1.570	+2.518	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

IRX4 by TAGAP expression — LARGE_INTESTINE

Explore this box plot interactively →