Across TCGA patient cohorts, TAFA5 protein abundance is significantly associated with the RNA expression of many other genes, with 5,548 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAFA5-associated genes across cancer lineages are KCNH5, GABRB2, and KCTD15. Each is linked with TAFA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA5-to-partner and partner-to-TAFA5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA5→partner) and Y-score (partner→TAFA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KCNH5 →	+0.788	+1.319	.003	<.001	3	2
GBM	GABRB2 →	+1.248	+1.272	<.001	<.001	3	2
LUAD	KCTD15 →	+1.047	+1.320	.002	<.001	3	2
GBM	RNF20 →	+0.501	+1.346	<.001	<.001	3	2
LUAD	MRPS22 →	+0.596	+1.503	<.001	.003	3	2
GBM	RGS7BP →	+1.575	+1.371	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,548 associations by consensus.

Exploration

TAFA5 survival (RNA) · tumor vs normal (RNA) · all TAFA5 data types