Across TCGA patient cohorts, TAFA5 mutation is significantly associated with the RNA expression of many other genes, with 1,446 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA5-associated genes across cancer lineages are RPL22P14, RNA5SP448, and RPS24P14. Each is linked with TAFA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAFA5-to-partner and partner-to-TAFA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA5→partner) and Y-score (partner→TAFA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL22P14 →	+0.124	+2.911	<.001	.005	3	3
CESC	RNA5SP448 →	+0.131	+4.357	<.001	.004	3	2
CESC	RPS24P14 →	+0.089	+3.013	.005	.002	3	2
CESC	GNG10P1 →	+0.090	+3.306	<.001	.006	3	2
CESC	TRAV28 →	+0.535	+2.930	<.001	.003	3	2
CESC	EIF4EBP1P1 →	+0.250	+3.741	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,446 associations by consensus.

Exploration

TAFA5 survival (RNA) · tumor vs normal (RNA) · all TAFA5 data types