TAFA4

Across TCGA patient cohorts, TAFA4 mutation is significantly associated with the RNA expression of many other genes, with 2,860 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA4-associated genes across cancer lineages are TFIP11, FBXO7, and SAMM50. Each is linked with TAFA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA4-to-partner and partner-to-TAFA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFIP11 grouped by TAFA4-low versus TAFA4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA4→partner) and Y-score (partner→TAFA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TFIP11 →	+0.407	+3.642	.004	.001	3	2
SKCM	FBXO7 →	+0.527	+2.816	.001	.001	3	2
SKCM	SAMM50 →	+0.546	+1.916	.002	.009	3	2
SKCM	TXN2 →	+0.349	+2.604	.002	<.001	3	2
SKCM	ACO2 →	+0.583	+3.623	<.001	.001	3	2
SKCM	RPAP1 →	+0.534	+3.182	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,860 associations by consensus.

TFIP11 by TAFA4 expression — SKCM

Explore this box plot interactively →