TAFA4

Across TCGA cell cohorts, TAFA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 726 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TAFA4-associated GO terms across cancer lineages are Extracellular structure organization, Calcium ion transmembrane transport, and Extracellular matrix organization. Each is linked with TAFA4 in more than 5 cancer types. Because this analysis shows association rather than direction, both TAFA4-to-partner and partner-to-TAFA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Extracellular structure organization grouped by TAFA4-low versus TAFA4-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA4→partner) and Y-score (partner→TAFA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Extracellular structure organization →	-0.072	-0.951	.003	.003	3	6
LUNG_NSCLC_LUSC	Calcium ion transmembrane transport →	-0.060	-0.173	.001	.004	3	6
LUNG_SCLC	Extracellular matrix organization →	-0.073	-1.093	.003	<.001	3	6
LUNG_SCLC	External encapsulating structure organization →	-0.071	-1.093	.003	<.001	3	6
LUNG_SCLC	Negative regulation of peptidase activity →	-0.300	-0.868	.008	.009	3	5
OVARY	Establishment of protein localization to organelle →	+0.041	+0.772	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 726 associations by consensus.

Extracellular structure organization by TAFA4 expression — LUNG_SCLC

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