TAFA4

Across TCGA cell cohorts, TAFA4 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible TAFA4-associated genes across cancer lineages are DCD, TBC1D21, and CCER1. Each is linked with TAFA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA4-to-partner and partner-to-TAFA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCD grouped by TAFA4-low versus TAFA4-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA4→partner) and Y-score (partner→TAFA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DCD →	+0.068	+4.977	.001	.007	3	1
LARGE_INTESTINE	TBC1D21 →	+0.020	+6.022	<.001	.001	3	1
LARGE_INTESTINE	CCER1 →	+0.012	+4.977	<.001	.007	3	1
LARGE_INTESTINE	PYDC2 →	+0.145	+5.415	<.001	.004	3	1
STOMACH	NPVF →	+0.015	+4.285	<.001	.007	3	1
STOMACH	PRSS38 →	+0.022	+4.794	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

DCD by TAFA4 expression — SKIN

Explore this box plot interactively →