TAFA4

Across TCGA cell cohorts, TAFA4 mutation is significantly associated with the mutation status of many other genes, with 432 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAFA4-associated genes across cancer lineages are TYRO3, CDK5RAP3, and PPP1R8. Each is linked with TAFA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA4-to-partner and partner-to-TAFA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TYRO3 grouped by TAFA4-low versus TAFA4-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA4→partner) and Y-score (partner→TAFA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TYRO3 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	CDK5RAP3 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	PPP1R8 →	+6.014	+6.014	.001	.001	1	2
LARGE_INTESTINE	DYNC1LI2 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	TMX1 →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	CER1 →	+4.523	+5.087	.006	.006	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 432 associations by consensus.

TYRO3 by TAFA4 expression — BLOOD_Lymphoma

Explore this box plot interactively →