Across TCGA pan-cancer cohorts, TAFA3 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated TAFA3 data layer compared with 29 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TAFA3 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAFA3 expression acts as an unfavorable survival marker.

HNSC are the cancer types where TAFA3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.088	0.712	<.001	28	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: TAFA3 tumor-vs-normal RNA expression · all TAFA3 data types