Across TCGA patient cohorts, TAFA3 mutation is significantly associated with the RNA expression of many other genes, with 275 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA3-associated genes across cancer lineages are NUTF2P8, F8A2, and MIR6744. Each is linked with TAFA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA3-to-partner and partner-to-TAFA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA3→partner) and Y-score (partner→TAFA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NUTF2P8 →	+0.151	+2.982	<.001	.003	3	1
UCEC	F8A2 →	+0.026	+3.109	.001	.007	3	1
UCEC	MIR6744 →	+0.168	+3.923	<.001	.009	3	1
UCEC	TRBV13 →	+0.625	+3.736	.002	.002	3	1
UCEC	RPS29P32 →	+0.452	+2.599	<.001	.009	3	1
SKCM	RNU7-113P →	+0.788	+4.160	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 275 associations by consensus.

Exploration

TAFA3 survival (RNA) · tumor vs normal (RNA) · all TAFA3 data types