Across TCGA patient cohorts, TAFA3 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA3-associated genes across cancer lineages are CD8+ Tcm, Fibroblasts, and MSC. Each is linked with TAFA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA3-to-partner and partner-to-TAFA3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA3→partner) and Y-score (partner→TAFA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.026	+2.350	.008	.031	3	2
HNSC	Fibroblasts →	+0.057	+5.339	<.001	.047	3	1
UCEC	MSC →	-0.226	-3.459	.031	.005	3	1
UCEC	pDC →	+0.048	+2.839	.048	.034	3	1
UCEC	CD8+ naive T-cells →	+0.038	+2.823	.005	.036	2	1
UCEC	Class-switched memory B-cells →	-0.065	-3.459	.023	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

TAFA3 survival (RNA) · tumor vs normal (RNA) · all TAFA3 data types