TAFA2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TAFA2 mutation is significantly associated with the RNA expression of many other genes, with 2,056 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA2-associated genes across cancer lineages are LSM3, TEFM, and RNU2-63P. Each is linked with TAFA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAFA2-to-partner and partner-to-TAFA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA2→partner) and Y-score (partner→TAFA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLSM3 →+0.592+2.523<.001<.00134
UCECTEFM →+0.429+2.601.001<.00133
UCECRNU2-63P →+0.336+1.914.008<.00133
UCECCUTC →+0.379+2.158<.001<.00133
UCECYTHDF3-AS1 →+0.676+2.839<.001.00132
BLCABMS1P14 →+0.076+5.177<.001.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,056 associations by consensus.

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