Across TCGA patient cohorts, TAFA2 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA2-associated genes across cancer lineages are EGFR_pY1068, A-Raf_pS299, and FASN. Each is linked with TAFA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA2-to-partner and partner-to-TAFA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA2→partner) and Y-score (partner→TAFA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.286	-2.700	.002	.005	3	1
UCEC	A-Raf_pS299 →	-0.212	-2.807	<.001	.003	3	1
UCEC	FASN →	+0.421	+2.906	.004	.001	3	1
UCEC	FoxM1 →	+0.255	+2.169	.008	.003	3	1
UCEC	FOXO3a_pS318_S321 →	-0.125	-2.077	.007	.005	3	1
UCEC	Gab2 →	+0.390	+1.874	.003	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

TAFA2 survival (RNA) · tumor vs normal (RNA) · all TAFA2 data types