Across TCGA cell cohorts, TAFA2 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAFA2-associated genes across cancer lineages are SMCP, DEFB125, and CT47A6. Each is linked with TAFA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA2-to-partner and partner-to-TAFA2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA2→partner) and Y-score (partner→TAFA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SMCP →	+0.034	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	DEFB125 →	+0.032	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	CT47A6 →	+0.103	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	USP17L4 →	+0.006	+5.209	.006	.005	3	1
SKIN	TMEM95 →	+0.034	+4.977	<.001	.007	3	1
LARGE_INTESTINE	MSGN1 →	+0.106	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

TAFA2 survival (RNA) · tumor vs normal (RNA) · all TAFA2 data types