Across TCGA patient cohorts, TAFA1 mutation is significantly associated with the RNA expression of many other genes, with 1,883 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAFA1-associated genes across cancer lineages are SKA1, SEC13, and SNF8. Each is linked with TAFA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA1-to-partner and partner-to-TAFA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA1→partner) and Y-score (partner→TAFA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA1 →	+0.622	+2.609	.001	.005	3	2
UCEC	SEC13 →	+0.485	+3.839	<.001	<.001	3	2
SKCM	SNF8 →	+0.344	+2.913	.004	.001	3	2
UCEC	MED27 →	+0.384	+2.312	.001	.001	3	2
SKCM	DBF4B →	+0.463	+3.488	.001	.002	3	2
UCEC	PEF1 →	+0.293	+2.769	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,883 associations by consensus.

Exploration

TAFA1 survival (RNA) · tumor vs normal (RNA) · all TAFA1 data types